Events & Publications
Upcoming and Past Events
ProteoGenex has attended numerous scientific conferences to stay up to date on current research, and to discuss our clients’ research needs one-on-one.
You can find us at these upcoming conferences:
The 24th International Molecular Medicine Tri-Conference – San Francisco, CA
February 19-24th, 2017
Booth #218
Publications
ProteoGenex has provided specimens used in hundreds of peer-reviewed research publications.
Don’t see your publication here? Let us know!
2024
- POS0464 SERUM PROTEOMIC ANALYSIS IDENTIFIES MARKERS ASSOCIATED WITH ANTI-CD19 CAR T THERAPEUTIC RESPONSE IN AUTOIMMUNE DISEASES.BMJ Journals. (2024): 1131-1132.
- Deciphering the exact sequence of endogenous soluble B cell maturation antigen and unbiased quantitation in multiple myeloma patient samples by LC-MS. Clinical Chemistry. 2024 Jan;70(1):339-49.
- Type IX Collagen Turnover Is Altered in Patients with Solid Tumors. Cancers.2024 May 27;16(11):2035.
- High throughput Surface Epitope Immunoaffinity Isolation of Extracellular Vesicles and Downstream Analysis. Biology Methods and Protocols. 2024 May 17:bpae032.
- Abstract PO2-13-08: Cell-free orphan noncoding RNAs and AI enable early detection of invasive breast cancer and ductal carcinoma in-situ. Cancer Research. 2024 May 2;84(9_Supplement):PO2-13.
- Automated immunoassay of serum NY-ESO-1 and XAGE1 antibodies for predicting clinical benefit with immune checkpoint inhibitor (ICI) in advanced non-small cell lung cancer. Cancer Treatment and Research Communications. 2024 Jun 28:100830.
- Deciphering functional tumor–immune crosstalk through highly multiplexed imaging and deep visual proteomics. Cancers. 2024:2024-05.
- Comparison of Tumor Binding Across Tumor Types and Cell Lines to Support Free Drug Considerations for Oncology Drug Discovery. Journal of Pharmaceutical Sciences. 2024 Mar 1;113(3):826-35.
- Preclinical evaluation of novel folate receptor 1-directed CAR T cells for ovarian cancer. Cancers. 2024 Jan 12;16(2):333.
- Differential Serum Peptidomics Reveal Multi-Marker Models That Predict Breast Cancer Progression. Cancers. 2024 Jan;16(13):2365.
2023
- Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation. Cell Metab. 2023 Aug 8; 35, 1457-1473.
- Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun. 2023 Jan 24; 14(383).
- Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering. J Immunother Cancer. 2023 Mar 14; 11(3).
- Robust and High-Throughput Analytical Flow Proteomics Analysis of Cynomolgus Monkey and Human Matrices with Zeno SWATH Data-Independent Acquisition. Mol Cell Proteomics. 2023 May 2; 22(6): 100562.
- Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000. Clin Epigenetics. 2023 Aug 14; 15: 130.
- High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma. Front Mol Biosci. 2023 Mar 10; 10: 1158058.
- Autoreactivity against Denatured Type III Collagen Is Significantly Decreased in Serum from Patients with Cancer Compared to Healthy Controls. Int J Mol Sci. 2023 Apr 11; 24(8): 7067.
- A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1or mutated NPM1. Cancer Cell Int. 2023 Feb 25; 23: 36.
- CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia. Front Oncol. 2023 May 1; 13:1150149.
- Levels of type XVII collagen (BP180) ectodomain are elevated in circulation from patients with multiple cancer types and is prognostic for patients with metastatic colorectal cancer. BMC Cancer. 2023 Oct 6; 23: 949.
- A novel biomarker of MMP-cleaved cartilage intermediate layer protein-1 is elevated in patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. Sci Rep. 2023 Dec 7; 13: 21717.
- A fragment of type VI collagen alpha-6 chain is elevated in serum from patients with atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus … Sci Rep. 2023 Feb 21; 13:
- Chromatin remodeling factor, INO80, inhibits PMAIP1in renal tubular cells via exchange of histone variant H2A.Z. for H2A. Sci Rep. 2023 Aug 14; 13:13235.
- Performance of the cobas EZH2 mutation test on clinical samples from non-Hodgkin lymphoma patients. PLoS One. 2023 Dec 14; 18(12).
- Ultra High-plex Spatial Proteogenomic Investigation of Giant Cell Glioblastoma Multiforme Immune Infiltrates Reveals Distinct Protein and RNA Expression Profiles. Cancer Res Commun. 2023 May 3; 3(5):763-779.
- Ayako Kakiuchi, Atsuhiko Kato, Shuji Hayashi, Izumi Yanagisawa, Ryo Konno, Sachiho Netsu, Tadashi Sankai. Composition for prophylaxis or treatment of IL-8 related diseases; U.S. Patent US11780912B2, issued October 10, 2023.
- Cherylle Goebel, Christopher Louden, Thomas C Long. Plasma based protein profiling for early stage lung cancer diagnosis; U.S. Patent US11780912B2, issued September 09, 2023.
2022
- Type XXII collagen complements fibrillar collagens in the serological assessment of tumor fibrosis and the outcome in pancreatic cancer. Cells. 2022 Nov 24; 11(23).
- Rho-associated, coiled-coil–containing protein kinase 1 regulates development of diabetic kidney disease via modulation of fatty acid metabolism. Kidney Int. 2022 Sept;102(3): 536-545.
- High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging. Nat Biotechnol. 2022 Oct 6, 40: 1794–1806.
- Advances in mixed cell deconvolution enable quantification of cell types in spatial transcriptomic data. Nat Commun. 2022 Jan 19;13(1):385.
- Automated next-generation profiling of genomic alterations in human cancers. Nat Commun. 2022 May 20; 13: 2830.
- ROCK2-induced metabolic rewiring in diabetic podocytopathy. Commun Biol. 2022 Apr 8;5(1):341.
- Type XX Collagen Is Elevated in Circulation of Patients with Solid Tumors. Int J Mol Sci. 2022 Apr 8;23(8):4144.
- A Highly Sensitive Biomarker of Type II Collagen C-Terminal Pro-Peptide Associated with Cartilage Formation. Int J Mol Sci. 2022 Dec 27; 24(1), 454.
- Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA. BMC Med. 2022 Nov 25; 20 (458).
- Holliday junction recognition protein as a prognostic biomarker and therapeutic target for oral cancer. Int J Oncol. 2022 Feb 1;60(3):26.
- Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer. Int J Oncol. 2022 Feb 1;60(3):27.
- Proteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues. Front Immunol. 2022 Dec 12; 13:1032716
- Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human … Journal of Virology. 2022 Sept 28, 96(18).
- Biomarker candidates for tumors identified from deep-profiled plasma stem predominantly from the low abundant area. J Proteome Res. 2022 May 23; 21(7): 1718-1735.
- Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test. Commun Med. 2022 March 17; 29(2)
- The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies. Sci Rep. 2022 Aug 16; 12, 13876.
- MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors. Sci Rep. 2022 Feb 3; 12, 1911.
- Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma. Oncotarget. 2022 Aug 3; 13, 960-967.
- Shiro Kitano, Kei Tsukamoto, Shinji Irie. Method and kit for assessing possibility of cancerization; US Patent US11492652B2, issued November 08, 2022.
2021
- Comparison of In Situ Hybridization, Immunohistochemistry, and Reverse Transcription-Droplet Digital Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing in Tissue. Arch Pathol Lab Med, 2021 Jul 1;145(7):785-796.
- A novel automated immunoassay for serum NY-ESO-1 and XAGE1 antibodies in combinatory prediction of response to anti-programmed cell death-1 therapy in non-small-cell lung cancer. Clin Chim Acta. 2021 Aug;519:51-59.
- Evaluation of a novel biomarker of type XXVIII collagen formation, PRO-C28, in samples from cancer and heart failure with preserved ejection fraction patients. J Pharm Biomed Anal. 2021 Jul 16;204:114272.
- CD11b + CTLA4 + myeloid cells are a key driver of tumor evasion in colorectal cancer. J Immunother Cancer. 2021 Jul;9(7):e002841.
- STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases. Eur Heart J. 2021 Jul 6;ehab249.
- Comparison of In Situ Hybridization, Immunohistochemistry, and Reverse Transcription-Droplet Digital Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing in Tissue. Arch Pathol Lab Med, 2021 Jul 1;145(7):785-796.
- CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia. Leukemia. 2021 Jun;35(6):1610-1620.
- NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells. Cell Rep Med. 2021 May 18;2(5):100279.
- Gingipains Identified in Alzheimer’s Disease Brains Differentially Fragment ApoE Proteins. Cell Reports Medicine. 34 Pages Posted: 3 May 202
- Construction of in vitro patient-derived tumor models to evaluate anticancer agents and cancer immunotherapy. Oncol Lett. 2021 May;21(5):406.
- Genome oligopaint via local denaturation fluorescence in situ hybridization. Mol Cell. 2021 Apr 1;81(7):1566-1577.e8.
- Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer. J Cancer 2021; 12(18):5385-5393.
- Tripeptide IRW Upregulates NAMPT Protein Levels in Cells and Obese C57BL/6J Mice. J Agric Food Chem. 2021 Feb 10;69(5):1555-1566
- Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer. Clin Epigenetics. 2021 Jan 21;13(1):14.
- Dual-Antigen System Allows Elimination of False Positive Results in COVID-19 Serological Testing. Diagnostics (Basel). 2021 Jan 11;11(1):102.
2020
- A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 Dec 2; 11(1):6161.
- Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer. J Immunother Cancer, 2020 May 24; 8(1): e000272.
- The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma. Cell Death Disease. 2020 October 23; 11, 902.
- Analytical performance evaluation of a commercial next generation sequencing liquid biopsy platform using plasma ctDNA, reference standards, and synthetic … BMC Cancer. 2020 October 1; 20(1):945.
- Blood test shows high accuracy in detecting stage I non-small cell lung cancer. BMC Cancer. 2020 Feb 21;20(1):137.
- Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes. Sci Rep. 2020 April 3; 10, 5894.
- Interobserver Reliability of Programmed Cell Death Ligand-1 Scoring Using the VENTANA PD-L1 (SP263) Assay in NSCLC. J Thorac Oncol. 2020 April; 15(4):550-555.
- Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles. Stem Cell Res Ther. 2020 Nov 2;11(1):463.
- Teclistamab is an active T cell-redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma. Blood Adv. 2020 Sep 22;4(18):4538-4549.
- A T-cell-redirecting bispecific G-protein-coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma. Blood. 2020 Apr 9;135(15):1232-1243.
- Comparison of continuous measures across diagnostic PD-L1 assays in non-small cell lung cancer using automated image analysis. Mod Pathol. 2020 Mar; 33(3):380-390.
- Analysis of Minor Acidic N-Glycans in Human Serum. J Proteome Res. 2020 Aug 7;19(8):3033-3043.
- Serum Type XIX Collagen is Significantly Elevated in Non-Small Cell Lung Cancer: A Preliminary Study on Biomarker Potential. Cancers (Basel). 2020 Jun 9;12(6):1510.
- The lncRNAH19 alleviates muscular dystrophy by stabilizing dystrophin. Nat Cell Biol. 2020 Nov;22(11):1332-1345.
- Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. PLoS One. 2020 Mar 11;15(3):e0229445.
- K. Stephen Suh, Ayala Tamir, Andrew L. Pecora. Serine proteases as biomarkers for ovarian cancer; US Patent US10662478B2, issued May 26, 2024.
2019
- Non-invasive profiling of protease-specific elastin turnover in lung cancer: biomarker potential. J Cancer Res Clin Oncol. 2019 February;145(2):383-392.
- Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma. Clin Cancer Res. 2019 June 1; ;25(11):3259-3265.
- Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model. J Cell Mol Med. 2019 October; 23(10): 7063–7077.
- Reliable Gene Expression Profiling from Small and Hematoxylin and Eosin-Stained Clinical Formalin-Fixed, Paraffin-Embedded Specimens Using the HTG EdgeSeq Platform. J Mol Diagn. 2019 September;21(5):796-807.
- β6 –integrinserves as a novelserumtumor marker for colorectal carcinoma. Int J Cancer. 2019 Aug 1;145(3):678-685.
- CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells. Int J Cancer. 2019 Mar 15;144(6):1367-1378.
- Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury. Cell Rep. 2019 Oct 29;29(5):1261-1273.e6.
- Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. BMC Med Genomics. 2019 Jan 10;12(1):7.
- Vastatin (the NC1 domain of human type VIII collagen a1 chain) is linked to stromal reactivity and elevated in serum from patients with colorectal cancer. Cancer Biol Ther. 2019 January 9;20(5):692-699.
- Extramitochondrial cardiolipin suggests a novel function of mitochondria in spermatogenesis. J Cell Biol. 2019 May 6;218(5):1491-1502.
- PTEN-inducedpartial epithelial-mesenchymal transition drives diabetic kidney disease.J Clin Invest. 2019 Mar 1;129(3):1129-1151.
- A quantitative method for detection of circulating fms related tyrosine kinase 3 (FLT-3) in acute myeloid leukemia (AML) patients. J Immunol Methods. 2019 Jul;470:55-58.
- Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts. Oncol Res. 2019 Aug 8;27(8):945-956.
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Diagnosis of Non-small Cell Lung Cancer for Early Stage Asymptomatic Patients. Cancer Genomics Proteomics. Jul-Aug 2019;16(4):229-244.
- Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders. Transl Oncol. 2019 Feb;12(2):368-374.
- Combination lenalidomide-rituximab immunotherapy activates anti-tumour immunity and induces tumour cell death by complementary mechanisms of action in follicular lymphoma. Br J Haematol. 2019 Apr;185(2):240-253.
- Assessment of PD-L1 mRNA and protein expression in non-small cell lung cancer, head and neck squamous cell carcinoma and urothelial carcinoma tissue specimens using RNAScope and immunohistochemistry. PLoS One. 2019 Apr 15;14(4):e0215393.
- Post-translational modifications of vimentin reflect different pathological processes associated with non-small cell lung cancer and chronic obstructive pulmonary disease. Oncotarget. 2019 Nov 26;10(63):6829-6841.
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Andrea Mahr, Toni Weinschenk, Colette Song, Oliver Schoor, Jens Fritsche, Harpreet Singh. Uterine cancer treatments; US Patent US10266581B2, issued April 23, 2024.
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Timothy S. Lewis, Che-Leung Law. Anti-NTB-A antibodies and related compositions and methods. US Patent US10435468B2, issued October 8, 2019.
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Ekkehard Schutz, Julia Beck, Howard Urnovitz. Prostate cancer associated circulating nucleic acid biomarkers. US Patent US10214775B2, issued February 26, 2019.
2018
- The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain. Mol Neurobiol. 2018 Mar;55(3):2420-2430.
- Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis. J Immunother Cancer. 2018 Mar 6;6(1):20.
- Transferring a Quantitative Molecular Diagnostic Test to Multiple Real-Time Quantitative PCR Platforms. J Mol Diagn. 2018 Jul;20(4):398-414.
- Tumstatin, a Matrikine Derived from Collagen Type IVα3, is Elevated in Serum from Patients with Non-Small Cell Lung Cancer. Transl Oncol. 2018 Apr;11(2):528-534.
- Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay. Diagn Pathol. 2018 Jul 24;13(1):47.
- Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue. Diagn Pathol. 2018 Oct 20;13(1):83.
- Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large B-cell lymphoma. Oncotarget. Oct 5;9(78):34644-34657.
- Direct molecular dissection of tumor parenchyma from tumor stroma in tumor xenograft using mass spectrometry-based glycoproteomics. Oncotarget. May 29;9(41):26431-26452.
- Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity. Cell Rep. 2018 Aug 14;24(7):1790-1801.
- Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. Cell Discov. 2018 Apr 3;4:15.
- A novel algorithm to improve specificity in ovarian cancer detection. Cancer Treat Res Commun. 2018;15:32-35.
- Multiplex Immuno-Liquid Chromatography-Mass Spectrometry-Parallel Reaction Monitoring (LC-MS-PRM) Quantitation of CD8A, CD4, LAG3, PD1, PD-L1, and PD-L2 in Frozen Human Tissues. J Proteome Res. 2018 Nov 2;17(11):3932-3940.
- Bead-linked transposomes enable a normalization-free workflow for NGS library preparation. BMC Genomics. 2018 Oct 1;19(1):722.
- Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer. Int J Oncol. 2018 Jan;52(1):155-165.
2017
- Andreas Bader, Jane Zhao; Biomarkers of mir-34 activity; U.S. Patent 20,140,378,528, issued December 25, 2014.
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Christina N. Carrigan, Kathleen R. Whiteman, Gillian Payne, and Sharron Ladd; Methods for increasing efficacy of FOLR1 cancer therapy; U.S. Patent 20,140,363,453, issued December 11, 2014.
- Kirsten M. Timms, Victor Abkevich, Elisha Hughes, Chris Neff, Julia Reid, Brian Morris, Saritha Kalva, Jennifer Potter, Thanh V Tran, Jian Chen, Diana Iliev, Zaina Sangale, Eliso Tikishvili, Michael Perry, Andrey Zharkikh, Alexander Gutin, Jerry S Lanchbury (2014); Association of BRCA1/2 defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes; Breast Cancer Research. 16(6): 475. doi:10.1186/s13058-014-0475-x
- Ayala Tamir, Ushma Jag, Sreeja Sarojini, Craig Schindewolf, Takemi Tanaka, Rajendra Gharbaran, Hiren Patel, Anil Sood, Wei Hu, Ruzeen Patwa, Patrick Blake, Polina Chirina, Jin Oh Jeong, Heejin Lim, Andre Goy, Andrew Pecora, K Stephen Suh (2014); Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes;Journal of ovarian research. 7(1): 109. doi:10.1186/s13048-014-0109-z
- Nolen, Brian M., Aleksey Lomakin, Adele Marrangoni, Liudmila Velikokhatnaya, Denise Prosser, Anna E. Lokshin (2014); Urinary protein biomarkers in the early detection of lung cancer; Cancer Prevention Research. 8(2):111-9. doi:10.1158/1940-6207.CAPR-14-0210
- Lyndi Rice, Michelle Pusey, Ewa Wandzioch; PME-1 AS A BIOMARKER TO PREDICT AND DIAGNOSE AN INCREASED RISK OF ENDOMETRIAL CANCER AND GENE SILENCING OF PME-1 TO INHIBIT EPITHELIAL TO MESENCHYMAL TRANSITION; U.S. Patent 20,140,323,546, issued October 30, 2014.
- Robert S. Puskas, Douglas Held. METHODS OF DIAGNOSING CANCER IN A PATIENT; U.S. Patent 20,140,315,194, issued October 23, 2014.
- Cheng Ai, Rujian Jiang, Li Fu, Youdong Chen (2014); MicroRNA-495 mimics delivery inhibits lung tumor progression; Tumor Biology. 36(2): 729-35. doi:10.1007/s13277-014-2687-1
- Martin Kerr, Helen E. Scott, Blaz Groselj, Michael RL Stratford, Katalin Karaszi, Naomi L. Sharma, Anne E. Kiltie (2014); Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer;Clinical Cancer Research. 20(21): 5435-5445. doi:10.1158/1078-0432.CCR-14-0542
- Alexander J. Burdette, Rene Alvarez (2014); Evaluation of Innate Immune Biomarkers in Saliva for Diagnostic Potential of Bacterial and Viral Respiratory Infection; NAVAL MEDICAL RESEARCH UNIT FINAL REPORT# 2014-005.
- Nicholas Willumsen, Cecilie L. Bager, Diana J. Leeming, Victoria Smith, Claus Christiansen, Morten A. Karsdal, David Dornan, Anne‐Christine Bay‐Jensen (2014); Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer; Cancer medicine. 3(5): 1136-1145. doi:10.1002/cam4.303
- Ewa Wandzioch, Michelle Pusey, Amy Werda, Sophie Bail, Aishwarya Bhaskar, Mariya Nestor, Jing-Jing Yang, Lyndi M. Rice (2014); PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells; Cancer research. 74(16): 4295-4305. doi:10.1158/0008-5472.CAN-13-3130
- Misato Hashizume, Masahiko Mihara (2014); Combination of High-Molecular-Weight Hyaluronic Acid and Cytokine Inhibitor Potently Inhibits Expression of Joint-Damage-Related Genes Induced By Synovial Fluid of RA Patients; J Arthritis. 3(1). doi:10.4172/2167-7921.1000117
- Xuemei Zhao, Liliana Delgado, Russell Weiner, Omar F. Laterza (2014); An ultra-sensitive clinical biomarker assay: quantitation of thymus and activation-regulated chemokine in human plasma;Bioanalysis. 6(8): 1069-1080. doi:10.4155/bio.14.72
- Sabine M. Brouxhon, Stephanos Kyrkanides, Xiaofei Teng, M. Kerry O’Banion, Robert Clarke, Stephen Byers, Li Ma (2014); Soluble‐E‐cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers; Molecular carcinogenesis. 53(11): 893-906. doi:10.1002/mc.22048
- Douglas White, Douglas Horejsh, Zhiyang Zeng, Tetsuo Uyeda, Poncho Meisenheimer, Molly Accola, William Rehrauer, Marjeta Urh (2014); A novel method for efficient and hands-free purification of circulating DNA from human plasma; Cancer research. 74: 1872. 1. doi:10.1158/1538-7445.AM2014-1872
- Suchit Jhunjhunwala, Zhaoshi Jiang, Eric W Stawiski, Florian Gnad, Jinfeng Liu, Oleg Mayba, Pan Du, Jingyu Diao, Stephanie Johnson, Kwong-Fai Wong, Zhibo Gao, Yingrui Li, Thomas D Wu, Sharookh B Kapadia, Zora Modrusan, Dorothy M French, John M Luk, Somasekar Seshagiri, Zemin Zhang (2014);Diverse modes of genomic alterations in hepatocellular carcinoma; Genome biology. 15(8): 436. doi:10.1186/s13059-014-0436-9
- Robert S. Puskas, Douglas Held (2014); Measurement of pka for cancer characterization; US Patent App. 14/114,811, filed April 18, 2012. Published August 21, 2014.
- Susanne K Pedersen, Susan M Mitchell, Lloyd D Graham, Aidan McEvoy, Melissa L Thomas, Rohan T Baker, Jason P Ross, Zheng-Zhou Xu, Thu Ho, Lawrence C LaPointe, Graeme P Young, Peter L Molloy (2014); CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia; Epigenetics. 9(8): 1071-1082. doi:10.4161/epi.29046
- J. Ryan Stanfield, Stacy Bamberg (2014); Durability evaluation of biopolymer coating on titanium alloy substrate; Journal of the mechanical behavior of biomedical materials. 35: 9-17. doi:10.1016/j.jmbbm.2014.03.003
- Lawrence Charles Lapointe, Susanne Kartin Pedersen, Peter Molloy (2014); Method of diagnosing neoplasms; US Patent App. 14/115,698, filed May 4, 2012. Published June 5, 2014.
- Adam S Adler, Mark L McCleland, Sharon Yee, Murat Yaylaoglu, Sofia Hussain, Ely Cosino, Gabriel Quinones, Zora Modrusan, Somasekar Seshagiri, Eric Torres, Vivek S Chopra, Benjamin Haley, Zemin Zhang, Elizabeth M Blackwood, Mallika Singh, Melissa Junttila, Jean-Philippe Stephan, Jinfeng Liu, Gregoire Pau, Eric R Fearon, Zhaoshi Jiang, Ron Firestein (2014); An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth; Genes & development. 28(10): 1068-1084. doi:10.1101/gad.237206.113
- Jinfeng Liu, Mark McCleland, Eric W Stawiski, Florian Gnad, Oleg Mayba, Peter M Haverty, Steffen Durinck, Ying-Jiun Chen, Christiaan Klijn, Suchit Jhunjhunwala, Michael Lawrence, Hanbin Liu, Yinan Wan, Vivek Chopra, Murat B Yaylaoglu, Wenlin Yuan, Connie Ha, Houston N Gilbert, Jens Reeder, Gregoire Pau, Jeremy Stinson, Howard M Stern, Gerard Manning, Thomas D Wu, Richard M Neve, Frederic J de Sauvage, Zora Modrusan, Somasekar Seshagiri, Ron Firestein, Zemin Zhang (2014);Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer; Nature communications. 5. doi:10.1038/ncomms4830
- Kathy Liszewski (2014); Discovering More Telling Biomarkers; Genetic Engineering & Biotechnology News. 34(9): 28-31. doi:10.1089/gen.34.09.16
- Cristiana Guiducci, Karen L. Fearon, Franck Barrat (2014); Human toll-like receptor inhibitors and methods of use thereof; US Patent App. 13/842,861, filed March 15, 2013. Published April 3, 2014.
- MT Lokant, RK Naz (2014); Presence of PSA auto‐antibodies in men with prostate abnormalities (prostate cancer/benign prostatic hyperplasia/prostatitis); Andrologia. 47(3): 328-332. doi:10.1111/and.12265
- Jing Wu, Jianhui Zhu, Haidi Yin, Ronald J. Buckanovich, David M. Lubman (2014); Analysis of glycan variation on glycoproteins from serum by the reverse lectin-based ELISA assay; Journal of proteome research. 13(4): 2197-2204. doi:10.1021/pr401061c
- Rolf Søkilde, Martin Vincent, Anne K. Møller, Alastair Hansen, Poul E. Høiby, Thorarinn Blondal, Boye S. Nielsen, Gedske Daugaard, Søren Møller, Thomas Litman (2014); Efficient identification of miRNAs for classification of tumor origin; The Journal of Molecular Diagnostics 16(1): 106-115. doi:10.1016/j.jmoldx.2013.10.001
- Barbra Sasu, Mitsuru Haniu, Thomas Charles Boone, Xiao-Juan Bi, Grace Ki Jeong Lee, Tara Arvedson, Aaron George Winters, Keegan Cooke, Jackie Z. Sheng (2014); Hepcidin, hepcidin antagonists and methods of use; US Patent No. 8629250, filed January 30, 2008. Published January 14, 2014.
- David Galas, Kai Wang, Paul Wilmes (2014); Complex rna composition of bodily fluids; US Patent App. 13/916,461, filed Jun 12, 2013. Published January 2, 2014.
- Anita K Gandhi, Derek Mendy, Michelle Waldman, Gengxin Chen, Emily Rychak, Karen Miller, Svetlana Gaidarova, Yan Ren, Maria Wang, Michael Breider, Gilles Carmel, Afshin Mahmoudi, Pilgrim Jackson, Mahan Abbasian, Brian E Cathers, Peter H Schafer, Tom O Daniel, Antonia Lopez‐Girona, Anjan Thakurta, Rajesh Chopra (2014); Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity;British journal of haematology. 164(2): 233-244. doi:10.1111/bjh.12622
2016
- MAIT cells are activated during human viral infections. Nat Commun. 2016 Jun 23;7:11653.
- An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics. Drug Metab Dispos. 2016 Oct;44(10):1692-6.
- Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chem Biol. 2016 Sep 16;11(9):2529-40.
- Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens. BMC Cancer. 2016 Jul 7;16:398.
- Type VIII collagen is elevated in diseases associated with angiogenesis and vascular remodeling. Clin Biochem. 2016 Aug;49(12):903-8.
- Hongbo Gu, Ailan Guo, Daniel Mulhern, Jeffrey C. Silva, and Jing Zhou (2016); Methylation and Acetylation Sites; S. Patent Application no. 14/884327. Published May 19, 2016.
- Haiying Wang, Yuqiu Jiang, and Yixin Wang (2016); Highly sensitive method for detecting low frequency mutations; Patent Application no. 14/375894. Published May 12, 2016.
- Jo-anne Hongo, Weiguang Mao, Paul Polakis, Andrew Polson, Rajesh Vij, Yan Wu, and Wei-ching Liang (2016); Anti-LGR5 antibodies and immunoconjugates; S. Patent Application no. 14/856731. Published April 14, 2016.
- Stephen K. Suh, Ayala Tamir, and Andrew L. Pecora (2016); Serine proteases as biomarkers for ovarian cancer; S. Patent Application no. 14/838945. Published April 7, 2016.
- The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer. J Ovarian Res. 2016 Mar 31;9:20.
- A Plasma-Based Protein Marker Panel for Colorectal Cancer Detection Identified by Multiplex Targeted Mass Spectrometry. Clin Colorectal Cancer. 2016 Jun;15(2):186-194.e13.
- Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models. Mol Cancer Ther. 2016 May;15(5):1132-44.
- Christopher K Raymond, Lee P Lim, Christopher D Armour (2016); Methods for quantitative genetic analysis of cell free dna; U.S. Patent no. 20160053301. Published February 25, 2016.
- Moraxella catarrhalis Evades Host Innate Immunity via Targeting Cartilage Oligomeric Matrix Protein. J Immunol. 2016 Feb 1;196(3):1249-58.
- The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes. BMC Bioinformatics. 2016 Jan 11;17 Suppl 1(Suppl 1):6.
- The three isoforms of hepcidin in human serum and their processing determined by liquid chromatography-tandem mass spectrometry (LC-tandem MS). Int J Hematol. 2016 Jan;103(1):34-43.
2015
- Timothy S Lewis, Che-leung Law (2015); Anti-NTB-A antibodies and related compositions and methods; U.S. Patent no. 20150376276. Published December 31, 2015.
- Boye Schnack Nielsen, Stine Jørgensen, Jan Skouv, Adam Baker, and Søren Møller (2015); In situ hybridization method and buffer; U.S. Patent no. 9212390. Published December 15, 2015.
- Quantitative Profiling of Post-translatonal Modifications by Immunoaffinity Enrichment and LC-MS/MS in Cancer Serum without Immunodepletion. Mol Cell Proteomics. 2015 Dec 3;15(2):692-702.
- Mark C Herzberg, Karen Farnie Ross, Brent R Sorenson (2015); Non-transgene transfection for therapeutic purposes; U.S. Patent no. 20150344537. Published December 3, 2015.
- Lyndi M Rice, Michelle Pusey (2015); PME-1 as a biomarker to predict and diagnose endometrial and breast cancer and …; U.S. Patent no. 20150284723. Published October 8, 2015.
- Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use. Clin Cancer Res. 2015 Oct 7; 22(4):1000-10.
- Stephen K Suh, Andre Goy (2015); Fibroblast growth factor-2 (fgf2) and syndecan-1 (sdc1) as biomarkers for poor …; U.S. Patent Application 14/640824, filed March 6, 2015. Published September 10, 2015.
- Cristiana Guiducci, Karen L. Fearon, Franck Barrat (2015); Human toll-like receptor inhibitors and methods of use thereof; Dynavax Technologies Corporation. U.S. Patent Application 14/430876, filed September 27, 2013. Published September 10, 2015.
- Vascular endothelial growth factor directly stimulates tumour cell proliferation in non-small cell lung cancer. Int J Oncol. 2015 Sep;47(3):849-56.
- Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders. Clin Biochem. 2015 Nov;48(16-17):1083-8.
- Nazarius Saah Lamango (2015); Cancer Diagnosis by Measuring Polyisoprenylated Methylated Protein Methyl …; Florida Agricultural and Mechanical University (Tallahassee, FL, US). U.S. Patent Application 14/105890, filed December 13, 2013. Published June 18, 2015.
- Ekkehard Schutz, Julia Beck, Howard Urnovitz (2015); Prostate cancer associated circulating nucleic acid biomarker; Chronix Biomedical (San Jose, CA, USA). U.S. Patent Application 14/414882, filed December 7, 2012. Published June 18, 2015.
- Lawrence Charles Lapointe, Susanne K Pedersen, Rohan Baker, Snigdha Gaur, Melissa Thomas (2015); A method of screening for colorectal cancer; U.S. Patent 20,150,152,505, issued June 4, 2015.
- A novel algorithm to improve specificity in ovarian cancer detection. Cancer Treat Res Commun. 2018;15:32-35.
- A two-gene blood test for methylated DNA sensitive for colorectal cancer. PLoS One. 2015 Apr 30;10(4):e0125041.
- Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling. BMC Pulm Med. 2015 May 3;15:53.
- Patrick McHugh, David Buckley, Mark Johnson, David Finn (2015); Novel biomarkers of chronic neuropathic pain; The British Pain Society & The University of Huddersfield.
- Neutrophil Gelatinase-Associated Lipocalin and Matrix … J Neurol Neurophysiol. 2015 April 4; 6(278).
- B. Olga, Daniel Tavares, Julianto Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui; Monoclonal antibodies for detection of folate receptor 1. U.S. Patent Application 14/473,828, filed August 29, 2014. Published April 2, 2015.
- A clinical biomarker assay to quantitate thymic stromal lymphopoietin in human plasma at sub-pg/ml level. Bioanalysis. 2015;7(5):573-82.
- MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation. 2015 Mar 28;2(5):406-20.
- Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates. PLoS One. 2015 Mar 12;10(3):e0119141.
- Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma. Cancer Cell. 2015 Mar 9;27(3):327-41.
- High-sensitivity immunoassay with surface plasmon field-enhanced fluorescence spectroscopy using a plastic sensor chip: application to quantitative analysis of total prostate-specific antigen and GalNAcβ1-4GlcNAc-linked prostate-specific antigen for prostate cancer diagnosis. Anal Chem. 2015 Feb 3;87(3):1797-803.
- Brugia malayi infective larvae fail to activate Langerhans cells and dermal dendritic cells in human skin. Parasite Immunol. 2015 Feb;37(2):79-91.
- Sabine Brouxhon, Stephanos Kyrkanides (2015); Combination therapies including inhibitors of the extracellular domain of e- … ; US Patent App. 14/385,351, filed March 15, 2013. Published February 5, 2015
2014
- Andreas Bader, Jane Zhao; Biomarkers of mir-34 activity; U.S. Patent 20,140,378,528, issued December 25, 2014.
- Christina N. Carrigan, Kathleen R. Whiteman, Gillian Payne, and Sharron Ladd; Methods for increasing efficacy of FOLR1 cancer therapy; U.S. Patent 20,140,363,453, issued December 11, 2014.
- Association of BRCA1/2 defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes. Breast Cancer Res. 2014 Dec 5;16(6):475.
- Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes. J Ovarian Res. 2014 Dec 5;7:109.
- Urinary protein biomarkers in the early detection of lung cancer. Cancer Prev Res (Phila). 2015 Feb;8(2):111-9.
- Lyndi Rice, Michelle Pusey, Ewa Wandzioch; PME-1 as a biomarker to predict and diagnose an increased risk of endometrial … U.S. Patent 20,140,323,546, issued October 30, 2014.
- Robert S. Puskas, Douglas Held. Methods of diagnosing cancer in a patient; U.S. Patent 20,140,315,194, issued October 23, 2014.
- Deoxycytidine Kinase Expression Underpins Response to Gemcitabine in Bladder CancerdCK and Response to Gemcitabine in Bladder Cancer. Clin Cancer Res. 2014 Nov 1;20(21):5435-45.
- Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer. Cancer Med. 2014 Oct;3(5):1136-45.
- PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells. Cancer Res. 2014 Aug 15;74(16):4295-305.
- Combination of High-Molecular-Weight Hyaluronic Acid and Cytokine Inhibitor Potently Inhibits Expression of Joint-Damage-Related Genes Induced By Synovial Fluid … ; J Arthritis. 2014;. 3(1), 1-6.
- An ultra-sensitive clinical biomarker assay: quantitation of thymus and activation-regulated chemokine in human plasma. Bioanalysis. 2014 Apr;6(8):1069-80.
- Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014 Nov;53(11):893-906.
- A novel method for efficient and hands-free purification of circulating DNA from human plasma. Cancer research. 2014 April 7; 74: 1872. 1.
- Diverse modes of genomic alteration in hepatocellular carcinoma. Genome Biol. 2014 Aug 26;15(8):436.
- Robert S. Puskas, Douglas Held (2014); Measurement of pka for cancer characterization. US Patent App. 14/114,811, filed April 18, 2012. Published August 21, 2014.
- CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. Epigenetics. 2014 Aug;9(8):1071-82.
- Durability evaluation of biopolymer coating on titanium alloy substrate. J Mech Behav Biomed Mater. 2014 Jul;35:9-17.
- Lawrence Charles Lapointe, Susanne Kartin Pedersen, Peter Molloy (2014); Method of diagnosing neoplasms – ii. US Patent App. 14/115,698, filed May 4, 2012. Published June 5, 2014.
- An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. Genes Dev. 2014 May 15;28(10):1068-84.
- Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. Nat Commun. 2014 May 8;5:3830.
- Discovering More Telling Biomarkers. Genetic Engineering & Biotechnology News. 2014 May 1; 34(9): 28-31.
- Cristiana Guiducci, Karen L. Fearon, Franck Barrat (2014); Human toll-like receptor inhibitors and methods of use thereof; US Patent App. 13/842,861, filed March 15, 2013. Published April 3, 2014.
- Presence of PSA auto-antibodies in men with prostate abnormalities (prostate cancer/benign prostatic hyperplasia/prostatitis). Andrologia. 2014 Mar 12;47(3):328-332.
- Analysis of glycan variation on glycoproteins from serum by the reverse lectin-based ELISA assay. J Proteome Res. 2014 Apr 4;13(4):2197-204.
- Efficient identification of miRNAs for classification of tumor origin. J Mol Diagn. 2014 Jan;16(1):106-15.
- Barbra Sasu, Mitsuru Haniu, Thomas Charles Boone, Xiao-Juan Bi, Grace Ki Jeong Lee, Tara Arvedson, Aaron George Winters, Keegan Cooke, Jackie Z. Sheng (2014); Hepcidin, hepcidin antagonists and methods of use; US Patent No. 8629250, filed January 30, 2008. Published January 14, 2014.
- David Galas, Kai Wang, Paul Wilmes (2014); Complex rna composition of bodily fluids; US Patent App. 13/916,461, filed Jun 12, 2013. Published January 2, 2014.
- Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity. Br J Haematol. 2014 Jan;164(2):233-44.
2013
- Jo-Anne Hongo, Weiguang Mao, Paul Polakis, Andrew Polson, Rajesh Vij, Yan Wu, Wei-Ching Liang (2013); Anti-LGR5 antibodies and immunoconjugates; US Patent App. 13/853,620, filed Mar 29, 2013. Published December 19, 2013.
- Jeffrey Shelton, Kevin Kelnar, Stephanie Volz, Alex Adai, David Brown (2013); miRNA biomarkers of prostate disease; US Patent App. 12/785,216, filed May 21, 2010. Published December 3, 2013.
- ADAM17-mediated CD44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC. Cancer Med. 2013 Dec;2(6):793-802.
- Prognostic significance of FRA expression in epithelial cancers using AQUA(®) technology. 2013 Dec;7(6):933-46.
- Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma. Clin Cancer Res. 2013 Nov 15;19(22):6261-71.
- Analytical validation of the Oncotype DX prostate cancer assay – a clinical RT-PCR assay optimized for prostate needle biopsies. BMC Genomics. 2013 Oct 8;14:690.
- Detection of truncated HER2 forms in formalin-fixed, paraffin-embedded breast cancer tissue captures heterogeneity and is not affected by HER2-targeted therapy. Am J Pathol. 2013 Aug;183(2):336-43.
- Fibroblast growth factor-2 (FGF2) and syndecan-1 (SDC1) are potential biomarkers for putative circulating CD15+/CD30+ cells in poor outcome Hodgkin lymphoma patients. J Hematol Oncol. 2013 Aug 29;6:62.
- Ron Firestein, Adam Shultz (2013); Methods of using cdk8 antagonists; US Patent App. 13/769,105, filed February 15, 2013. Published August 22, 2013.
- Jun Tan, Demian Obregon, Huayan Hou, Juan Deng (2013); Use of Functional Autoantibodies in Alzheimer Disease; US Patent App. 13/768,158, filed February 15, 2013. Published August 22, 2013.
- Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci Transl Med. 2013 Aug 7;5(197):197ra103.
- Differential chemical derivatization integrated with chromatographic separation for analysis of isomeric sialylated N-glycans: a nano-hydrophilic interaction liquid chromatography-MS platform. Anal Chem. 2013 Sep 3;85(17):8421-8.
- Dimitri Semizarov, Xin Lu, Ke Zhang, Rick R Lesniewski (2013); Genomic classification of non-small cell lung carcinoma based on patterns of … US Patent App. 12/607,079, filed October 28, 2009. Published July 30, 2013.
- Dimitri Semizarov, Xin Lu, Ke Zhang, Rick R Lesniewski (2013); Genomic classification of colorectal cancer based on patterns of gene copy … US Patent App. 12/607,082, filed October 28, 2009. Published July 30, 2013.
- Sylvie Beaudenon-Huibregtse, Emmanuel Laborier, Laura Elizondo (2013); Micrornas differentially expressed in cervical cancer and uses thereof. US Patent App. 13/735,760, filed January 7, 2013. Published July 18, 2013.
- S100A8/A9 (calprotectin) negatively regulates G2/M cell cycle progression and growth of squamous cell carcinoma. PLoS One. 2013 Jul 9;8(7):e69395.
- TP53-independent function of miR-34a via HDAC1 and p21(CIP1/WAF1.). Mol Ther. 2013 Sep;21(9):1678-86.
- Gene expression analyses support fallopian tube epithelium as the cell of origin of epithelial ovarian cancer. Int J Mol Sci. .2013 Jul 1;14(7):13687-703.
- Development and validation of a microRNA-based diagnostic assay for classification of renal cell carcinomas. Mol Oncol. 2013 Jun;7(3):732-8.
- Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clin Cancer Res .2013 Jun 15;19(12):3234-46.
- Altered expression of sialylated glycoproteins in ovarian cancer sera using lectin-based ELISA assay and quantitative glycoproteomics analysis. J Proteome R.2013 Jul 5;12(7):3342-52.
- An extensive targeted proteomic analysis of disease-related protein biomarkers in urine from healthy donors. PLoS One. 2013 May 28;8(5):e63368.
- Analytic performance studies and clinical reproducibility of a real-time PCR assay for the detection of epidermal growth factor receptor gene mutations in formalin-fixed paraffin-embedded tissue specimens of non-small cell lung cancer. BMC Cancer. 2013 Apr 27;13:210.
- Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease. PLoS One. 2013 Apr 2;8(4):e60726.
- Paraoxonase-1 status in patients with hereditary hemochromatosis. J Lipid Res. 2013 May;54(5):1484-92.
- Allele-specific, non-extendable primer blocker PCR (AS-NEPB-PCR) for DNA mutation detection in cancer. J Mol Diagn. 2013 Jan;15(1):62-9.
- Xiao-Juan Bi, Grace Ki Jeong Lee, Jackie Z. Sheng (2013); Methods of producing hybridomas and monoclonal antibodies and antibodies …; US Patent App. 13/620,007, filed September 14, 2012. Published January 17, 2013.
- Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib.
PLoS One. 2013;8(1):e53733.
2012
- The complex exogenous RNA spectra in human plasma: an interface with human gut biota? PLoS One. 2012 Dec 10; 7(12):e51009.
- Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer. PLoS One. 2012 Oct 4; 7(10):e46823.
- Classification of the four main types of lung cancer using a microRNA-based diagnostic assay. J Mol Diagn. 2012 June 27; 14(5):510-7.
- Neuropilin-2 expression in cancer. Histopathology. 2012 Mar 2; 61(3):340-9.
- Rong A. Fan, Kirstin L. Krall (2012);PCan065 Antibody Compositions and Methods of Use; US Patent App. 12/904,709, filed October 14, 2010. Published May 8, 2012.
- The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML. Blood Cancer J. 2012 May 4;2(5):e69.
- Autoreactive-Aβ antibodies promote APP β-secretase processing. J Neurochem. 2012 Mar;120(5):732-40.
- TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties. Leukemia. 2012 Feb;26(2):236-43.
- Discovery and validation of molecular biomarkers for colorectal adenomas and cancer with application to blood testing. PLoS One. 2012 Jan 19;7(1):e29059.
- MicroRNA in situ hybridization. Methods Mol Biol. 2012;822:67-84.
- Neuropilin-1 expression in cancer and development. J Pathol. 2012 Jan;226(1):50-60.
- Polycomb repressor complex-2 is a novel target for mesothelioma therapy. Clin Cancer Res. 2012 Jan 1;18(1):77-90.
- The complex exogenous RNA spectra in human plasma: an interface with human gut biota? PLoS One. 2012 Dec 10;7(12):e51009.
- Allele-Specific, Non-Extendable Primer Blocker PCR (AS-NEPB-PCR) for DNA Mutation Detection in Cancer. J Mol Diagn. 2012 Nov 14;15(1):62-9.
- Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer. PLoS ONE. 2012 Oct 4. 7(10): e46823.
- Puskas, Robert (St. Louis, MO, US), Held, Douglas (St. Louis, MO, US); Combination methods of diagnosing cancer in a patient. United States Patent Application 20120231479; 09/13/2012.
- A multiplex serum protein assay for determining the probability of colorectal cancer. Am J Cancer Res. 2012 August 20;2(5):598-605.
- Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS. 2012 Sep 7;11(9):4541-52.
- 20-HETE-producing enzymes are up-regulated in human cancers. Cancer Genomics Proteomics. 2012 Jul-Aug;9(4):163-9.
- A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens. Br J Cancer. 2012 Jul 10;107(2):345-51.
- Blockade of IL-6 and TNF-α inhibited oxLDL-induced production of MCP-1 via scavenger receptor induction. Eur J Pharmacol. 2012 Aug 15;689(1-3):249-54.
- In situ validation of an intestinal stem cell signature in colorectal cancer. 2013 Jul;62(7):1012-23.
- Neil Crawford – 2012; Utilization of Methylation Levels Across the IGF2 Gene as a Predictive Marker for Various Types of Cancer; MQP-BIO-DSA-6547
- Quality Bio-Specimens for Novel Biomarker Discovery. Cancer Res. 2012 April 15; 72 (8_Supplement): 4099.
- Atherogenic effects of TNF-α and IL-6 via up-regulation of scavenger receptors. Cytokine. 2012 Jun;58(3):424-30.
- Deeb S, El-Nesr K, Mahdi E, El-Begawey ASaM. Technology and Application of Tissue Microarrays. Beni-Suef Univ J App Sciences. 2012; 1(1): 73-85.
- Do men with prostate abnormalities (prostatitis/benign prostatic hyperplasia/prostate cancer) develop immunity to spermatozoa or seminal plasma? 2012 Aug;35(4):608-15.
2011
- Li, Hongyan (Oak Park, CA, US), Breau, Alan (San Mateo, CA, US), Sasu, Barbra (Westlake Village, CA, US); Methods of isolating and/or analyzing hepcidin by mass spectrometry & medthods of quantifying hepcidin are disclosed.; App.: 13/160711; Pub Date: 12/22/2011;
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Discovery and validation of molecular biomarkers for colorectal adenomas and cancer with application to blood testing. PLoS One. 2012;7(1):e29059.
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Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia. Blood Cancer J. 2011 Nov;1(11):e44.
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Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer. 2009 Oct 20;9:374.
- Agnes Rafalko, Shujia Dai, William S. Hancock, Barry L. Karger & Marina Hincapie; Development of a Chip/Chip/SRM platform using digital chip isoelectric focusing & LC-Chip mass spectrometry for enrichment & quantitation of low abundance protein biomarkers in human plasma.; J. Proteome res., Just Accepted Manuscript. DOI: 10.1021/pr2006704. Publication date (Web): Nov. 21, 2011.
- Mijung Kim, Lisa Rooper, Jia Xie, Andrew Kajdacsy-Balla & Maria V Barbolina; Fractalkine Receptor CX3CR1 is Expressed in Epithelial Ovarian Carcinoma Cells & Required for Motility & Adhesion to Peritoneal Mesothelial Cells; Molecular Cancer Research: Published OnlineFirst Nov. 7, 2011; doi: 10.1158/1541-7786.MCR-11-0256.
- Lamango, Nazarius Saah; Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity: US Patent 8053207, Posted on Freepatentsonline.com.
- Mariana Guergova-Kuras, Istvan Kurucz, William Hempel, Nadege Tardieu, Janos Kadas, Carole Malderez-Bloes, Anne Jullien, Yann Kieffer, Marina Hincapie, Andras Guttman, Eszter Csanky, Balazs dezso, Barry L. Karger & Laszlo Takacs; Discovery of lung cancer biomarkers by profiling the plasma proteome with monoclonal antibody libraries: Molecular & Cellular Proteomics, 1st Published on Sept. 26, 2011 (doi: 10.1074/mcp.M111.010298; mcponline.org).
- Tri-Hung Nguyen. Evis Havari, Rajashree MvLaren, Mindy Zhang, Yide Jiang, Stephen L. Madden, Bruce Roberts, Johanne Kaplan, Srinivas Shankara; Alemtuzumab Induction of Intracellular Signaling & Apoptosis in Malignant B Lymphocytes; Informa Heathcare Issue TOC, Posted Online Sept. 14,2011 (doi:10.3109/10428194.2011.623253).
- Adrian M. Jubb, Laura A. Strickland, Scot D. Liu, Judy Mak, Maike Schmidt, Hartmut Koeppen;Neuropilin-1 Expression in Cancer & Development:Copyright 2011 Pathological Society of Great Britian & Ireland. Published by John Wiley & Sons Ltd. DOI 10.1002/path.2989
- Free Patents Online; PCan065 Antibody Compositions & Methods of Use; US patent Application 20110159516.
- Foltz, M Gallo, K Cooke, RR Ketchem; The invention relates to monoclonal antibodies that bind hepcidin and methods of making and using such antibodies. Also provided are methods of treating hepcidin-related disorders; US Patent 20,110,150,888, 2011.
2010
- K. Guze, M. Short, H. Zeng, M. Lerman, S. Sonis: Comparison of molecular images as defined by Raman spectra between normal mucosa & squamous cell carcinoma in the oral cavity. 7 Dec 2010 DOI: 10.1002/jrs.2838.
- Dongdong Wang, Marina Hincapie, Tomas Rejtar, and Barry L. Karger; Ultrasensitive Characterization of Site-Specific Glycosylation of Affinity-Purified Haptoglobin from Lung Cancer Patient Plasma Using 10 μm i.d. Porous Layer Open Tubular Liquid Chromatography−Linear Ion Trap Collision-Induced Dissociation/Electron Transfer Dissociation Mass Spectrometry; Barnett Institute and Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States. Publication Date (Web): February 21, 2011.
- Kim, Phillip (Irvine, CA, US), Liu, Xinjun (San Diego, CA, US), Kirkland, Richard (San Diego, CA, US), Lee, Tani (San Diego, CA, US), Ybarrondo, Belen (San Diego, CA, US), Singh, Sharat (Rancho Sata Fe, CA, US):Biomarkers For Determining Sensitivity of Breast Cancer Cells to HER2-Targeted Therapy; US Patent App., Publication Date; 3/24/2011.
- Sinicorpi, Dominick;Morlan, John: The invention to methods of depleting RNA from a nucleic acid sample. The RNA may be any RNA, including, but not limited to, rRNA, tRNA, & Mrna. The method is useful for depleting RNA from nucleic acid sample obtained from a fixed paraffin-embedded tissue (FPET) sample. The metod may also be used to prepare cDNA, in particular, a library for further analysis or manipulation. US Patent App., Publication Date; 5/12/2011.
- Zhi Zeng, Marina Hincapie, Sharonn J. Petteri, Samir M. Hanash, Joost Schalkwijk, Jason M. Hogan, Hong Wang & William Hancock; A Proteomics Platform Combining Depletion, Multi-Iectin Affinity Chromatography _M-LAC) & Isoelectric Focusing to study the Breast Canver Proteome; DOI: 10.1021/2002802 – Publication Date April 22, 2011.
- CL Chang, JJ Cai, C Lo, J Amigo; Adaptive selection of an incretin gene in Eurasian populations;Genome Res.January 2011 21: 21-32.
- Dongdong Wang, Marina Hincapie, Mariana Guergova-Kuras, Janos Kadas, Laszlo Takacs & Barry L. Karger; Antigen Identification & Characterization of Lung Cancer Specific Monoclonal Antibodies Produced by mAB Proteomics; J. Proteome Res., 2010, 9(4), pp 1834-1842.
- N Wild, H Andreas, W Rollinger & F Krause; A combination of serum markers for the early detection of colorectal cancer; Clinical Cancer Resclincanres .0119.2010.
- JF Wiggins, L Ruffino, K Kelner & M Omotola; Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34; Cancer Res July 25, 2010 70:5923-5930.
- POST AUTHOR CORRECTIONS, 6 OCTOBER 2010; A Robust Immunohistochemical Assay for Detecting PTEN Expression in Human Tumors;Applied Immunohistochemistry & Molecular Morphology doi: 10.1097/PAI.0b013e3181f1da13.
- K. Gandhi, A; Kang, J.; Capone, L.; Parton, A.; Wu, L.; H. Zhang, L.; Mendy, D.; Lopez-Girona, A.; Tran, T.; Sapinoso, L.; Fang, W.; Xu, S.; Hampton, G..; B. Bartlett, J. Schafer, P.; Dexamethasone Synergizes with Lenalidomide to Inhibit Multiple Myeloma Tumor Growth, But reduces Lenalidomide-Induced Immunomodulation of T & NK Cell Function; Current Cancer Drug Targets, Volume 10, Number 2.
- Sascha Tierling, Matthias Schuster, Reimo Tetzner & Jorn Walter; A combined HM-PCR/SNuPE method for high sensitive detection of rare DNA methylation; Epigenetics Chromatin. 2010; 3:12.
- Barbra J. Sasu, hongyan Li, Mark J. Rose, Tara L. Arvedson, George Doellgast & Graham Molineux; Serum hepcidin but not prohepcidin may be an effective marker for anemia of inflammation; Blood Cells, Molecules, & diseases volume 45, Issue3, 15 October 2010, pages 238-245.
- Beaulieu, Martin PhD; Desaulniers, Marie RN; Bertrand, Nicolas MSc; Deschesnes, Rena G. Phd; Beaudry, Guillaume MSc; Garon, Genevieve MSc; Haince, Jean-Francois PhD; Houde, Michel PhD; Holzer, Timothy J. PhD; Analytical Performance of a qRT-PCR Assay to Detect Guanylyl Cyclases C in FFPE Lymph Nodes of Patients With Colon Cancer; Diagnostic Molecular Pathology March 2010 – Volume 19 – Issue 1.
- Russell M. Walker, David I. Lichter, William L. Trepicchio & Elena Izmailova; Evaluation of BRAF V600E mutation detection assays for purpose of clinical tumor sample analysis; Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Develoment – Sep 27-30, 2010 Denver CO
- Jean-Francois Haince, Michel Houde, Guillaume Beaudry, Sylvain L’Esperance, Genevieve Garon, Marie Desaulniers, Laurie J Hafer, James I Heald, Stephen Lyle, Steven R. Grossman, Bernard Tetu, Daniel J. Sargent & Yves Fradet; Comparison of histopathology & RT-qPCR amplification of guanylyl cyclase C for detection of colon cancer metastases in lymph nodes; Journal of Clinical Pathology 2010; 63;530-537.
- Xin Lu, Ke Zhang, Charles Van Sant, John Coon & Dimitri Semizarov; An algorithm for classifying tumors based on genomic aberrations & selecting representative tumor models; BMC Medical Genomics 2010 Volume 3:23.
- Stine Jorgensen, Adam baker, Soren Moller & Boye Schnack Nielsen; Robust one-day in situhybridization protocol for detection of microRNAs in paraffin samples using LNA probes; MethodsVolume 52, Issue 4, Dec. 2010, Pages 375-381.
- John Morlan, Joffre baker, Dominick Sinicropi; Mutation Detection by Real-Time PCR: A Simple, Robust & Highly Selective Method.
2009
- Georg Wieczorek, Anne Asemissen, Fabian Model, Ivana Turbachova, Stefan Floess, Volker Liebenberg, Udo Baron, Diana Stauch, Katja Kotsch, Johann Pratschke, Alf Hamann Christoph Loddenkeper, Harald Stein, Hans Dieter Volk, Ulrich Hoffmuller, Andreas Grutzkau, Alexander Mustea, Jochen Huehn, Carmen Scheibenbogen & Sven Olek; Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in peripheral Blood & Solid Tissue; doi: 10.1158/0008-5472.CAN-08-2361Cancer Res January 15, 2009 69, 599.
- Mark Watson, Anne Roulston, Laurent Belec, Xavier Billot, Richard Marcellus, Dominique Bedard, Cynthia Beriner, Stephane Branchaud, Helen Chan, Kenza Dairi, Karine Gilbert, Daniel Goulet, Michel-Oliver Gratton, Henady Isakau, Anne Janu Abdelkrim Khadir, Elizabeth Koch, Manon Lavoie Michael Lawless, Mai Nguyen, Denis Paquette, Emile Turcotte, Alvin Berger, Matthew Michell, Gordon C. Shore & Pierre Beauparlant; The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid PhosphoribosyItransferase1-Deficient Tumors; Molecular & Cellular Biology, Nov 2009, p. 5872-5888 Vol. #29, No. 21.
2008
- Lei Wu, Mary Adams, Troy Carter, Roger Chen, George Muller, David Stirling, Peter Schafer & J. Black Bartlett;Lenalidomide Enhances Natural Killer Cell & Monocyte-Mediated Antibody-Dependent Cellular Cytotoxicity of Rutuximab-Treated CD20+ Tumor Cells. doi: 10.1158/1078-0432.CCR-07-4405 Clin Cancer Res July 15, 2008 14;4650.
- Yuqiu Jiang, Graham Casey, Ian C. Lavery, Yi Zhang, Dmitri Talantov, Michelle Martin-McGreevy, Marek Skacel, Elena Manilich, Abhijit Mazumder, David Atkins, Conor P. Delaney, and Yixin Wang; Development of a Clinically Feasible Molecular Assay to Predict Recurrence of Stage II Colon Cancer. Journal of Molecular Diagnostics 2008, Vol. 10(4), 346-354.
- Catherine I. Dumur, Maureen Lyons-Weiler, Christin Sciulli, Carleton T. Garrett, Iris Schrijver, Tara K. Holley, Juan Rodriguez-Paris, Jonathan R. Pollack, James L. Zehnder, Melissa Price, Jill M. Hagenkord, C. Ted Rigl, Ljubomir J. Buturovic, Glenda G. Anderson, and Federico A. Monzon;Interlaboratory Performance of a Microarray-Based Gene Expression Test to Determine Tissue of Origin in Poorly Differentiated and Undifferentiated Cancers. Journal of Molecular Diagnostics 2008, Vol. 10(1), 67-77.
2007
- Joern Lewin, Achim Plum, Thomas Hildmann, Tamas Rujan, Florian Eckhardt, Volker Liebenberg, Catherine Lofton-Day, and Reinhold Wasserkort;Comparative DNA methylation analysis in normal and tumour tissues and in cancer cell lines using differential methylation hybridization. Int J Biochem Cell Biol 2007, Vol. 39(7-8), 1539-50.
- John D. Carpten, Andrew L. Faber, Candice Horn, Gregory P. Donoho, Stephen L. Briggs, Christiane M. Robbins, Galen Hostetter, Sophie Boguslawski, Tracy Y. Moses, Stephanie Savage, Mark Uhlik, Aimin Lin, Jian Du, Yue-Wei Qian, Douglas J. Zeckner, Greg Tucker-Kellogg, Jeffrey Touchman, Ketan Patel, Spyro Mousses, Michael Bittner, Richard Schevitz, Mei-Huei T. Lai, Kerry L. Blanchard, and James E. Thomas; A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature 2007 448, 439-444.
2006
- Xiao-Jun Ma, PhD; Rajesh Patel, PhD; Xianqun Wang, PhD; Ranelle Salunga, BSc; Jaji Murage, BSc; Rupal Desai, BSc; J. Todd Tuggle, BSc; Wei Wang, PhD; Shirley Chu, BSc; Kimberly Stecker, BSc; Rajiv Raja, PhD; Howard Robin, MD; Mat Moore, PhD; David Baunoch, PhD; Dennis Sgroi, MD; Mark Erlander, PhD;Molecular Classification of Human Cancers Using a 92-Gene Real-Time Quantitative Polymerase Chain Reaction Assay.Archives of Pathology and Laboratory Medicine 2006 130(4), 465-473.
- Dondapati Chowdary, Jessica Lathrop, Joanne Skelton, Kathleen Curtin, Thomas Briggs, Yi Zhang, Jack Yu, Yixin Wang, and Abhijit Mazumder;Prognostic Gene Expression Signatures Can Be Measured in Tissues Collected in RNAlater Preservative. J Mol Diagn. 2006, Vol. 8(1), 31-39.
- Dimitri Talantov, Jonathan Baden, Tim Jatkoe, Kristina Hahn, Jack Yu, Yashoda Rajpurohit, Yiqiu Jiang, Chang Choi, Jeffrey S. Ross, David Atkins, Yixin Wang, and Abhijit Mazumder; A Quantitative Reverse Transcriptase-Polymerase Chain Reaction Assay to Identify Metastatic Carcinoma Tissue of Origin. J Mol Diagn. 2006, Vol. 8(3), 320-329.
2005
- Caridad Rosette, Richard B. Roth, Paul Oeth, Andreas Braun, Stefan Kammerer, Jonas Ekblom, and Mikhail F. Denissenko; Role of ICAM1 in invasion of human breast cancer cells. Carcinogenesis 2005, Vol. 26(5), 943-950.
- Dmitri Talantov, Abhijit Mazumder, Jack X. Yu, Thomas Briggs, Yuqiu Jiang, John Backus, David Atkins, and Yixin Wang; Novel Genes Associated with Malignant Melanoma but not Benign Melanocytic Lesions. Clinical Cancer Research 2005, Vol. 11, 7234-7242.